Skip to content

Efficacy of Adding Acetaminophen to Preemptive Multimodal Analgesia in Pediatric Osteotomy Correction Surgery

Efficacy of Adding Acetaminophen to Preemptive Multimodal Analgesia in Pediatric Osteotomy Correction Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095363
Enrollment
Unknown
Registered
2025-01-06
Start date
2025-01-08
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Osteotomy Correction Surgery

Interventions

Preemptive analgesia group:In the preemptive analgesia group, pediatric patients received an intravenous infusion of Paracetamol Injection 30 minutes before the skin incision at a dose of 15 mg/kg (eq
Conventional group:In the conventional group, children received an intravenous infusion of 0.9% sodium chloride solution 30 minutes before the skin incision at a dose of 1.5 ml/kg. The infusion was al

Sponsors

Hunan Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1) Aged 6-18 years (school age); 2) Patients undergoing elective osteotomy; 3) Primary surgery; 4) American Society of Anesthesiologists (ASA) grade ?-?

Exclusion criteria

Exclusion criteria: 1) Patients with an allergy to acetaminophen; 2) Patients with preoperative abnormalities in cardiopulmonary, liver, kidney, or coagulation function; 3) Patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency; 4) Patients with failed epidural puncture; 5) Patients with neurological or psychiatric disorders; 6) Patients with chronic pain conditions.

Design outcomes

Primary

MeasureTime frame
The incidence of moderate to severe pain within 72 hours postoperatively;

Secondary

MeasureTime frame
Heart rate,blood pressure, and oxygen saturation, and peak airway pressure during sugery;Pain Scores;Opioid Consumption;Postoperative PCIA (Patient-Controlled Intravenous Analgesia) Effective Presses;Rescue Analgesia Within 72 Hours Postoperatively;Postoperative subjective sleep quality ;

Countries

China

Contacts

Public ContactTing Xiao

Hunan Children's Hospital

39299652@qq.com+86 731 8560 0952

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026