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A Prospective Cohort Study Evaluating the Correlation Between MAIT Cell Functional Marker Expression in G-CSF Mobilized Donor Grafts and Post-Transplant Complications by Using Full-Spectrum Flow Cytometry

A Prospective Cohort Study Evaluating the Correlation Between MAIT Cell Functional Marker Expression in G-CSF Mobilized Donor Grafts and Post-Transplant Complications by Using Full-Spectrum Flow Cytometry

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095349
Enrollment
Unknown
Registered
2025-01-06
Start date
2024-01-04
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malignant hematologic diseases undergoing hematopoietic stem cell transplantation

Interventions

GVHD group and- non-GVHD group:NA

Sponsors

Peking University People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Healthy donors and paired allo-HSCT recipients treated at Peking University Institute of Hematology, 2. Between 18 and 60 years old; 3. Subjects are able to provide written informed consent.

Exclusion criteria

Exclusion criteria: Subjects who cannot comply with the study.

Design outcomes

Primary

MeasureTime frame
Graft-versus-host disease (GVHD);—

Secondary

MeasureTime frame
Infection;Relapse;Non-relapsed mortality (NRM);Overall survival(OS);—

Countries

China

Contacts

Public ContactXiaosu Zhao

Peking University People’s Hospital

zhao.xiaosu@outlook.com+86 135 0122 2226

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 17, 2026