Postpartum depression
Conditions
Interventions
Dexmedetomidine group:10 minutes (± 5 minutes) after delivery of the fetus, 50ug (0.1ml of dexmedetomidine) is given to the woman nasally.
Normal saline group:10 minutes (±5 minutes) after delivery of the fetus, the same volume of saline spray is given to the mother through the nose.
Sponsors
Third Xiangya Hospital, Central South University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) >= 18 years old; (2) Gestation greater than 28 weeks; (3) No serious cardiovascular and cerebrovascular diseases; (4) The mother can communicate well with the follow-up; (5) Voluntarily participate in this study and sign relevant informed consent. (6) Prenatal EPDS score >= 10 points.
Exclusion criteria
Exclusion criteria: (1) Contraindications and allergies to the use of dexmedetomidine; (2) have unstable mental illness; (3) Severe cardiovascular and cerebrovascular diseases; (4) Unable to understand the language of the follow-up and unable to communicate well; (5) Parturients who are considered by the investigator to be unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of self-injurious thoughts;Sleep quality score;Sedation score;Comparison of Generalized Anxiety Disorder-7 score; | — |
Countries
China
Contacts
Public ContactSaiying Wang
Third Xiangya Hospital, Central South University
Outcome results
None listed