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Oxalidine in endoscopic gastrointestinal polypectomy in the elderly: a randomized, controlled, double-blind trial

Oxalidine in endoscopic gastrointestinal polypectomy in the elderly: a randomized, controlled, double-blind trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095332
Enrollment
Unknown
Registered
2025-01-06
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal disease

Interventions

O1 group:O1 group: oxalidine 0.01mg/kg+ propofol 1.5-2 mg/kg
O2 group:O2 group: oxalidine 0.02mg/kg+ propofol 1.5-2 mg/kg
SD group:SD group: sufentanil 0.1ug/kg+ propofol 1.5-2 mg/kg

Sponsors

The Affiliated Panyu Central Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 100 Years

Inclusion criteria

Inclusion criteria: ? ASA grade I-III; ? age = 60 years old; ? patients undergoing elective gastrointestinal endoscopy and treatment; ? Informed consent to participate in this project.

Exclusion criteria

Exclusion criteria: ? Important organ dysfunction such as recent myocardial infarction or cerebral infarction, severe conduction block, malignant arrhythmia, important organ decompensation; ? Severe pulmonary infection or upper respiratory tract infection, status asthmaticus, severe apnea syndrome; ? the use of opioids before surgery; ?BMI>35kg/m^2; (5) alcohol or drug abuse, drug addiction and abuse; (6) a history of communication disorders (such as severe speech, hearing, and vision disorders).

Design outcomes

Primary

MeasureTime frame
Incidence of hypoxemia;Incidence of body movement;

Secondary

MeasureTime frame
Incidence of nausea and vomiting;Incidence of cough;An additional dose of propofol was given;

Countries

China

Contacts

Public ContactLin Yang

The Affiliated Panyu Central Hospital of Guangzhou Medical University

salinyangyl@163.com+86 159 1572 1012

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026