Chronic sinusitis
Conditions
Interventions
Propofol group:Propofol
Fospropofol disodium group:Fospropofol Disodium Injection
Sponsors
DALIAN NO.3 PEOPLE'S HOSPITAL
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 18 to 65 years old, no gender restriction; 2.American Society of Anesthesiologists (ASA) physical status classification: I-III; 3.Body Mass Index (BMI): 18.5 to 30 kg/m²; 4.Subjects requiring elective surgery under general anesthesia with an expected duration of surgery longer than 30 minutes; 5.Voluntary participation with signed informed consent;
Exclusion criteria
Exclusion criteria: 1.Subjects with contraindications to general anesthesia or a history of anesthesia accidents; 2.Subjects with craniocerebral injury, intracranial hypertension, stroke, unstable angina pectoris, or myocardial infarction; 3.Subjects with respiratory insufficiency, obstructive lung disease, difficult airway, or assessed as difficult tracheal intubation (Modified Mallampati Class III or IV); 4.Subjects with uncontrolled diabetes or hypertension; 5.Subjects with a history of drug abuse, alcoholism, or drug dependence; 6.Subjects with abuse or long-term use of anesthetics, sedatives, or analgesics; 7.Subjects with known or suspected allergy or contraindication to any component of the study drug or to sufentanil citrate injection, propofol, remifentanil hydrochloride injection, or fospropofol disodium injection specified in the protocol; 8.Subjects with a history of mental illness; 9.Subjects who have participated in any drug clinical trial within 1 month prior to screening; 10.Pregnant and lactating women; fertile women or men unwilling to use contraception throughout the trial period; study participants (including male participants) with plans to conceive within 1 month after the trial; 11.Subjects whom the investigator considers to have any other factors that make them unsuitable for participation in this trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in hemodynamic indices (SBP/DBP, MAP, HR, SpO2) and BIS values at various monitoring time points;; | — |
Countries
China
Contacts
Public ContactZhao Shiling
DALIAN NO.3 PEOPLE'S HOSPITAL
Outcome results
None listed