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Predictive role of cytokines in PD1/PDL1 inhibitor-related adverse events

Predictive role of cytokines in PD1/PDL1 inhibitor-related adverse events

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095319
Enrollment
Unknown
Registered
2025-01-06
Start date
2025-01-06
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant tumor

Interventions

case series:none

Sponsors

Ziyang Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Age >= 18 years old, gender not limited; Pathologically or clinically diagnosed as a malignant tumor, suitable for and first-time use of immune checkpoint inhibitors (PD1/PD-L1); Physical fitness ECOG <= 1 point; Understand and sign the informed consent form.

Exclusion criteria

Exclusion criteria: Known severe allergy to the study drug or any of its excipients; Conditions that are not suitable for ICIs treatment as specified in the 2023 version of the CSCO Guidelines for Immune Checkpoint Inhibitors. Activity or history of autoimmune disease or immunodeficiency; Treatment with systemic immunostimulants; Subjects deemed by the investigator to be unsuitable for ICIs treatment.

Design outcomes

Primary

MeasureTime frame
HR;

Secondary

MeasureTime frame
Sensitivity;Specificity;

Countries

China

Contacts

Public ContactJieyan Luo

Ziyang Central Hospital

20537389@qq.com+86 150 8260 8690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026