Damage to skin barrier after aesthetic medicine treatment
Conditions
Interventions
Non-ablative dot matrix laser therapy(test group):After non-ablative fractional laser treatment, apply the test product to half of the face according to the random table
Non-ablative dot matrix laser therapy(control group):After non-ablative fractional laser treatment, apply the control product to the other half of the face according to the random table
Non-crosslinked hyaluronic acid treatment(test group):After non-crosslinked hyaluronic acid treatment, apply the test product to half of the face according to the random table
Non-crosslinked hyaluronic acid treatment(control group):After non--crosslinked hyaluronic acid treatment, apply the control product to the other half of the face according to the random table
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.20-45 years old, a.Male or female. 2. Large pores and visible fine lines(Only non-ablative dot matrix laser therapy). 3. Willing to receive non-ablative fractional laser treatment or non-crosslinked hyaluronic acid treatment . 4. Can persist in completing the entire course of treatment. 5. Having already planned an aesthetic procedure.
Exclusion criteria
Exclusion criteria: 1. Those with a history of allergy to hyaluronic acid(Only non-crosslinked hyaluronic acid treatment). 2. Participants with a history of allergy to the laser type used in non-ablative fractional laser treatment(Only non-ablative dot matrix laser therapy). 3. Participants who currently have skin diseases, severe allergies, a history of treatment that may affect skin healing, a history of facial aesthetic treatments, etc(Only non-crosslinked hyaluronic acid treatment). 4. Participants with active skin infection or inflammation, especially in the treatment area(Only non-ablative dot matrix laser therapy). 5. participants with skin cancer or suspected skin cancer. 6. Participants who have received non-absorbable filler injections, laser treatments, facial implants, etc. in the past year(Only non-crosslinked hyaluronic acid treatment). 7. Participants who have received aesthetic treatment within 6 months(Only non-ablative dot matrix laser therapy). 8. Participants with serious systemic diseases, such as heart disease, poorly controlled diabetes, etc. 9. Women who are pregnant, breastfeeding, or planning pregnancy during treatment. 10. Participants with scar diathesis or history of abnormal healing. 11. People with sensitive skin(Only non-crosslinked hyaluronic acid treatment). 12. Participants with psychiatric disorders or other conditions that may affect treatment compliance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Loss of moisture through the epidermis; | — |
Secondary
| Measure | Time frame |
|---|---|
| redness value;moisture content of skin stratum corneum;Blood flow perfusion volume;Security assessment; | — |
Countries
China
Contacts
Public ContactWang Xi
West China Hospital, Sichuan University
Outcome results
None listed