Relationship between basal interleukin-6 levels and the incidence of maternal fever after epidural labor analgesia

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500095291

Enrollment

Unknown

Registered

2025-01-06

Start date

2025-01-11

Completion date

Unknown

Last updated

2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum fever

Interventions

Basic IL-6 normal group:NA

Elevated basal IL-6 group:NA

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) ASA Grades I-II (2) Age range: 18-40 years old (3) Body mass index= 37 weeks (5) Singleton primiparous women with head position (6) Require epidural analgesia and dilation of the cervix <= 5cm (7) No contraindications for epidural anesthesia (8) No pregnancy related diseases, such as pregnancy hypertension, and pregnancy diabetes requiring medication (9) No infectious disease (such as hepatitis B and syphilis) (10) Fetal heart rate monitoring before delivery analgesia showed no abnormalities (fetal heart rate range 120-160bpm) (11) Initial body temperature is normal (36.0-37.0 ?)

Exclusion criteria

Exclusion criteria: (1) Require the cervix to be greater than 5cm during delivery analgesia (2) Contraindications for spinal anesthesia (such as abnormal coagulation function and infection at the puncture site) (3) Individuals with difficulties in performing epidural procedures (such as scoliosis, ankylosing spondylitis) (4) Individuals who are allergic to the investigational drug, its shaping components, or other drugs used in this study are known (5) Those who use opioid drugs and other sedatives and analgesics within one week, those who use magnesium sulfate, and those who use antipyretic analgesics (6) Individuals with a history of drug abuse (7) Sleep apnea syndrome patients (8) Individuals with severe heart, lung, liver, and kidney dysfunction (9) Individuals with symptoms of infection (such as colds)

Design outcomes

Primary

Measure	Time frame
intrapartum fever;	—

Secondary

Measure	Time frame
basal body temperature;Body temperature during labor;Number of cervical examinations;Duration of labor process;Newborn Apgar;Cesarean section rate;	—

Countries

China

Contacts

Public ContactLu Yuanyuan

Huai'an Maternity and Child Healthcare Center

18762019265@163.com+86 187 6201 9265

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026