subclinical jaundice
Conditions
Interventions
Subclinical Jaundice Group:no
Healthy Control Group:no
Sponsors
The Second Affiliated Hospital of Baotou Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for subclinical jaundice are as follows: Serum bilirubin levels must be between 1 to 3 times the upper limit of the normal reference range, specifically total bilirubin between 17.1 to 51.3 umol/L, conjugated bilirubin between 3.42 to 10.26 umol/L, and unconjugated bilirubin between 13.68 to 41.04 umol/L. Participants should not have received any specific treatment within the three months leading up to the study. Except for bilirubin, lipids, and blood sugar indicators, all other liver and kidney function tests and routine blood tests must yield results within the normal range. Participants must be capable of understanding the study's objectives and procedures, be able to complete questionnaires and assessments of physiological and psychological health, and willingly sign an informed consent form. For the healthy control group, the criteria include: Age between 18 to 70 years old, with no gender restrictions. Bilirubin, lipids, blood sugar, and other liver and kidney function tests, as well as routine blood tests, must all fall within the normal range. Abdominal ultrasound results should be normal, with no evidence of fatty liver, cirrhosis, or other organic pathological changes. Participants should have no diagnosed clinical or chronic diseases such as hypertension, diabetes, coronary heart disease, etc.
Exclusion criteria
Exclusion criteria: Exclusion criteria for the subclinical jaundice group include all diseases that can cause abnormal bilirubin levels and any confirmed hepatobiliary system or other organic diseases, such as obstructive diseases (e.g., cholecystitis, post-cholecystectomy, gallbladder stones, bile duct stones), hepatocellular diseases (e.g., drug-induced liver injury, viral hepatitis, alcoholic liver disease), hemolytic diseases (e.g., hemolytic anemia), and other known organic diseases (e.g., congenital genetic diseases, malignant tumors). Additionally, abdominal ultrasound results must not indicate liver echo coarseness or cirrhosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unconjugated bilirubin;conjugated bilirubin;total bilirubin;Self-Rating Anxiety Scale;SATEDscale; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood lipids;Blood glucose;blood pressure;fatty liver;Helicobacter pylori infection;alcohol consumption;pickled foods;irregular diet;leftover food; | — |
Countries
China
Contacts
Public ContactNian Yuanyuan
The Second Affiliated Hospital of Baotou Medical College, Department of Gastroenterology
Outcome results
None listed