Gynecological disease
Conditions
Interventions
The ciprofol group:A single induction injection of 0.4 mg/kg, followed by an initial rate of 0.8 mg/kg/h for maintenance. The infusion rates of ciprofol adjusted to maintain a BIS of 40–60.
The propofol group:A single induction injection of 2.0 mg/kg, followed by an initial rate of 5.0 mg/kg/h for maintenance. The infusion rates of propofol adjusted to maintain a BIS of 40–60.
Sponsors
The First Affiliated Hospital, University of South China
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. aged 18–60 years; 2. classified with an American Society of Anesthesiologists (ASA) physical status of I–II; 3. scheduled for hysteroscopic surgery; 4. Able to understand the trial protocol and questionnaire content, with the patient or their legal representative signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with chronic alcoholism; 2. pregnant or breastfeeding patients; 3. history of allergy to benzodiazepines, opioids, propofol, or any sedative opioids; 4. uncontrolled hypertension; 5. severe heart, lung, liver, or kidney dysfunction; 6. psychiatric or neurological disorders were excluded. 7. Patients who are unable to communicate due to language barriers or other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic data ;Injection pain; | — |
Countries
China
Contacts
Public ContactHuan Yang
The First Affiliated Hospital, University of South China
Outcome results
None listed