Small cerebral vascular disease, stroke, cognitive impairment
Conditions
Interventions
Case groups:Stroke of cerebral small vessel disease
Control group:Stroke except of cerebral small vessel disease
Sponsors
Beijing Pinggu District Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years old, gender unlimited;Definite stroke diagnosis: transient ischemic attack, hemorrhagic stroke, ischemic stroke; 2.All patients included in the study completed a cognitive scale screening before enrollment,and those with normal scores were included in the study. 3.Case group patients met the diagnostic criteria for small cerebral vascular disease and had their first stroke; 4.Patients knowingly and voluntarily participate, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with prior cognitive dysfunction, abnormal scores on cognitive scales before inclusion in the study, and comorbidities that may lead to the development of certification disorder; 2. Patients who have used drugs that affect cognition (such as antipsychotic drug chlorpromazine, central anesthetic drug ketamine, benzodiazepine, diazepam, cholinergic receptor antagonist hyoscyamine, etc.) within the previous 2 weeks; 3. Diseases that cause elevated IGF-1 levels, such as cancer tumors, acne vulgaris, systemic lupus erythematosus, Henoch-Schonlein purpura, pathological purpura, systemic scleroderma, etc.; 4. Patients who are unable to complete the cognitive assessment of neurological function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Countries
China
Contacts
Public ContactFaxiu Shen
Beijing Pinggu District Hospital
Outcome results
None listed