Postoperative sleep disorders
Conditions
Interventions
low esketamine group (E1 group):Esketamine was given 0.5mg·kg-1 at the time of anesthesia induction, followed by 0.25 mg·kg-1·h-1 pumping injection immediately until the end of the operation.
high esketamine group (E2 group):Esketamine was given 0.5mg·kg-1 at the time of anesthesia induction, followed by 0.5 mg·kg-1·h-1 pumping injection immediately until the end of the operation.
Blank control group:Conventional general anesthesia induction + equal volume normal saline + conventional anesthesia + intraoperative continuous pumping injection of equal volume normal saline until t
Sponsors
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1)18 years old = age = 65 years old (2) ASA Class I or II (3) Proposed thoracoscopic lung resection surgery (4) Sign the informed consent form
Exclusion criteria
Exclusion criteria: (1) Allergic to anesthesia drugs (2) History of congestive heart failure (3) Severe arrhythmia exists (4) Presence of pre excitation syndrome (5) Existence of liver failure (6) Existence of renal failure (7) Previous mental illnesses such as anxiety, depression, or sleep disorders (8) I am currently taking psychiatric medication (9) Other reasons why researchers believe it is not appropriate to participate in this experiment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Athens Insomnia Scale;Numerical Rating Scale;vital signs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting;Whether there is coughing and coughing score after extubation to PACU exit;PACU staying time;General information including age, sex, body mass index, and duration of surgery; | — |
Countries
China
Contacts
Public ContactShangguan Wangning
Wenzhou Medical University Affiliated Stomatological Hospital
Outcome results
None listed