None listed
Conditions
Interventions
Experimental group ciprofol group (group C):During the induction period, ciprofol was slowly injected 0.3mg/kg intravenously
Control group propofol group (group P):2mg/kg propofol was slowly injected intravenously during the induction period.
Sponsors
Hebei Eye Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients with ASA grade I-III; 2.>=60 years old; 3.BMI18.5 ~ 29.9kg/m^2; 4.Patients undergoing general anesthesia with laryngeal mask for ophthalmology;
Exclusion criteria
Exclusion criteria: 1. There are contraindications of laryngeal mask application such as fullness of stomach, abnormal oropharyngeal structure and gastroesophageal reflux disease; 2. Suffering from severe cardiovascular and cerebrovascular diseases; 3. Patients with severe impairment of liver and kidney function, mental illness or cognitive dysfunction; 4. Patients who have been taking sedatives and analgesics for a long time and are allergic to the study drug; 5. Patients who expect surgery time to be too long (more than 4 hours) or too short (less than 30 minutes); 6. Hypertensive patients with drug control >=160/100mmHg;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamics(SBP?DBP?MAP?HR); | — |
Secondary
| Measure | Time frame |
|---|---|
| Depth of anesthesia;Incidence of adverse reactions;Quality of recovery (time to recovery and restlessness during recovery and PACU residence time);Cognitive function; | — |
Countries
China
Contacts
Public ContactFang Li
Hebei Eye Hospital
Outcome results
None listed