Skip to content

Randomized Trial of Ultrasound-Guided Ropivacaine Thoracic Paravertebral Nerve Block Combined with Dexmedetomidine forrolonging Postoperative Analgesia in Patients Undergoing Thoracoscopic Lung Cancer Resection

Randomized Trial of Ultrasound-Guided Ropivacaine Thoracic Paravertebral Nerve Block Combined with Dexmedetomidine forrolonging Postoperative Analgesia in Patients Undergoing Thoracoscopic Lung Cancer Resection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095250
Enrollment
Unknown
Registered
2025-01-03
Start date
2024-08-06
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Group C:Evaluation of postoperative and postextubation analgesic effects in patients undergoing radical lung cancer surgery under general anesthesia induction
Group TD:The effect of ropivacaine combined with dexmedetomidine thoracic paravertebral nerve block on postoperative and post-extub analgesia in patients under
Group T:The effect of ropivacaine thoracic paravertebral nerve block on postoperative and post-extubation pain relief in patients undergoing radical cancer su

Sponsors

Yuebei People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 65 years; 2. ASA grade ? ~ ?; 3. Both men and women can; 4. BMI18-24kg/m^2; 5. Preoperative examination of the heart, liver, kidney function without obvious abnormalities; 6. no previous history of local anesthetic allergy; 7. Complete follow-up data; 8. Patients had good cooperation and informed consent to the purpose and significance of the study.

Exclusion criteria

Exclusion criteria: 1. severe cardiopulmonary, liver and kidney dysfunction; 2. MVV% < 40, FEV1 < 1.0L; 3. Patients with chronic pain who need to take analgesics for a long time; 4. Coagulation dysfunction, infection or cancer at the puncture site; 5. Chronic alcoholism, opioid dependence; 6. Intraoperative thoracotomy; 7. Those who refuse to apply analgesic programs; 8. Patients with history of sinus; 9.Patients with incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
Perform the Post-Anesthesia Agitation Score after the patient regains consciousness;Including the time of the blocking plane fixed, the time of analgesia onset, and the number of blocked segments;Record the patient's postoperative analgesic effect.;

Secondary

MeasureTime frame
Assessment of Ramsay score after extubation;Hemodynamic parameters;

Countries

China

Contacts

Public ContactLiu Yuan

Yuebei People’s Hospital

1815956596@qq.com+86 15976251528

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026