non-fluent aphasia
Conditions
Interventions
Case group:None
Initiated iTBS group:cTBS+ iTBS
Non-initiated iTBS group:false cTBS+ iTBS
False Stimulus Group:false cTBS+ false iTBS
Healthy control group:None
Sponsors
Shanghai Second Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.All met the criteria of 'Diagnostic Points of Various Cerebrovascular Diseases' formulated by the Fourth National Conference on Cerebrovascular Diseases of the Chinese Medical Association in 1995; 2.Right-handed, non-fluent aphasia as assessed by Western Aphasia Battery (WAB) after the onset of the disease; 3.Duration of the disease from 2 weeks to 6 months; 4.Chinese as the first language, with an education level of primary school or above; 5.Ability to remain sitting independently for more than 30 min, can cooperate to complete the language function assessment and fNIRS test, and have no obvious memory and intellectual disabilities; 6.Patient or family members signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Concomitant other neurodegenerative diseases, such as Parkinson's disease, etc. 2. application of drugs that change the excitability of the cerebral cortex (antiepileptic drugs), sleeping pills, benzodiazepines, etc. 3. history of psychiatric anomalies; 4. epilepsy; 5. severe cardiac, hepatic, renal dysfunction or other serious physical diseases; 6. coma, unable to cooperate with the examination and treatment; 7. auditory or visual deficiencies that may affect the assessment and treatment; 8. According to the safety guideline, rTMS is not suitable for those who have metal foreign objects or other electronic devices implanted in the body.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Near Infrared (fNIRS) Detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Westemm Aphasia Battery; | — |
Countries
China
Contacts
Public ContactJiayi Xia
Shanghai Second Rehabilitation Hospital
Outcome results
None listed