None
Conditions
Interventions
Experimental group:Oats ß dextran, 2.5 g per day for the first week, 5 g per day from the second week, before or after meals, for 2 months
Sponsors
School of Public Health,Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Fully understand this study and voluntarily sign the informed consent form; 2. Aged over 18 years old; 3. Able to provide venous blood samples and stool samples; 4. Eating habits are relatively stable within one month before the intervention and during the intervention period.
Exclusion criteria
Exclusion criteria: 1. Unable to comply with the research protocol or research procedures; 2. Oral antibiotics within one month; 3. Had a gastrointestinal endoscopy within one month; 4. Suffering from irritable bowel syndrome, Crohn's disease or ulcerative colitis; 5. Take dietary fiber preparations, prebiotics and probiotic preparations within one month before intervention; 6. Allergic to oat ingredients; 7. Women who are pregnant (positive pregnancy test before taking the drug) or breastfeeding; 8. Clinically significant metabolic abnormalities, physical examination abnormalities or laboratory test abnormalities; 9. Subjects that the researcher believes are not suitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiome profile;Plasma metabolic profile; | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma cytokines;Peripheral blood lymphocyte ratio;Adverse reaction rate; | — |
Countries
China
Contacts
Public ContactLi Liu
Tongji Medical College of Huazhong University of Science and Technology
Outcome results
None listed