Rectal cancer, endometrial cancer, cervical cancer, and prostate cancer, among others
Conditions
Interventions
Experimental group:Remazolam was continuously pumped by 1mg/kg/h for anesthesia maintenance
Sponsors
The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age> 18 years old; 2.ASAI.~II; 3. Patients who intend to undergo lower abdominal and pelvic surgery under general anesthesia; 4.BMI >18kg/m2; 5. Patients or family members have a full understanding of the purpose and significance of this study, voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to the drug in this test 2. Patients with a history of cerebrovascular disease and preoperative intracranial hypertension; 3. Those with eye diseases and a history of eye surgery; 4. Patients with psychiatric diseases (such as schizophrenia, depression, etc.), history of epilepsy and cognitive dysfunction; 5. Those with a history of abuse of psychotropic drugs and narcotics in the past; 6. Suffering from severe vision or hearing disorders, unable to communicate smoothly, or illiterate; 7. ASA grade III or above, such as those with uncontrolled systemic diseases such as hypertension, diabetes, hyperthyroidism, patients with severe cardiopulmonary diseases, abnormal liver function, renal function, coagulation function, etc.; 8. Participated in other drug clinical trials as a subject in the past 3 months; 9. Subjects who, in the opinion of the investigator, have any other factors that are not suitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Optic nerve sheath diameter;Mean blood flow velocity of the middle cerebral artery;Middle cerebral artery pulsatility index;Middle cerebral artery resistance index; | — |
Countries
China
Contacts
Public ContactLu Xihua
Affiliated Cancer Hospital of Zhengzhou University (Henan Provincial Cancer Hospital)
Outcome results
None listed