knee osteoarthritis
Conditions
Interventions
control group:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for Patients with Knee Osteoarthritis (KOA) a) Meets the 2001 American College of Rheumatology diagnostic criteria for knee osteoarthritis: Patients with knee joint pain must have at least 3 of the following7 items: (1) Age >=50 years; (2) Morning stiffness = 50 years;(2) Morning stiffness <30 minutes; (3) Crepitus during joint movement; (4) Bony enlargement evident on knee examination; (5) Bone tenderness; (6) No significant synovial warmth; (7) ESR <40 mm/h; (8) Rheumatoid factor (RF) <1:40; (9) Synovial fluid shows signs of osteoarthritis. b) According to the numerical pain scale, the pain score in the past two weeks must not exceed 7. c) Able to independently complete a20-minute walk. d) No age limit. e) The ratio of male to female participants is approximately1:1. 2. Inclusion Criteria for Age-Matched Control Group (The inclusion of age-matched controls takes place after the inclusion of KOA patients, adopting a one-to-one matching approach to meet the following criteria): a) Non-knee osteoarthritis patients. b) No statistically significant age difference compared to knee osteoarthritis patients. c) No statistically significant differences in height and weight compared to knee osteoarthritis patients. d) Able to independently complete a20-minute walk. e) The ratio of male to female participants is approximately1:1.
Exclusion criteria
Exclusion criteria: a) History of knee joint surgery b) Traumatic injury c) Injuries to the torso, lower back, hip, leg, and ankle joints in the past three months d) Arthritis in the lower back, hip, and ankle joints e) Presence of neurological diseases f) Unable to walk independently without assistive devices (such as crutches or walkers) g) Other diseases affecting lower limb function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional near-infrared spectroscopy, fNIRS;Electromyograph;three-dimensional kinematics and kinetics; | — |
Secondary
| Measure | Time frame |
|---|---|
| WOMAC scale;Timed Up and Go test; | — |
Countries
China
Contacts
Public ContactZhuo Wang
West China Hospital, Sichuan University
Outcome results
None listed