Anterograde amnesia
Conditions
Interventions
Control group:NS infusion
Low dosage remimazolam group:0.075mg/kg induction+infusion
high dosage remimazolam group:0.15mg/kg induction+infusion
Sponsors
Shenzhen University General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1Age 18~65 years; 2BMI 18~28kg/m2; 3ASA I~III; 4Without obstructive sleep apnea syndrome; 5Selective operation with spinal anesthesia or nerve block anesthesia and operation duration>60min; 6sign the informed consent
Exclusion criteria
Exclusion criteria: 1Interventional surgery; 2breath difficult; 3mental disorders, cognitive dysfunction or serious systemic diseases; 4undergoing general anesthesia within 7 days before inclusion of the study; 5allergic to benzodiazepines, opioids, or other pharmaceutical ingredients; 6spinal anesthesia or nerve block anesthesia with difficults, unexpected long time and imperfect anesthesia effects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anterograde amnesia degree;(QoR-15) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| life signs;BIS;MOAA/S score;Complications; | — |
Countries
China
Contacts
Public ContactJun Xiong
Shenzhen University General Hospital, Shenzhen University
Outcome results
None listed