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Development of a Scoring Model for Patients with Central Nervous System Infections Based on Cerebrospinal Fluid Lactate Concentration

Development of a Scoring Model for Patients with Central Nervous System Infections Based on Cerebrospinal Fluid Lactate Concentration

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095199
Enrollment
Unknown
Registered
2025-01-03
Start date
2025-01-06
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute infection

Interventions

Bacterial meningitis group:none
viral meningitis group:none
tuberculous meningitis group:none
cryptococcal meningitis group:none

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to No maximum

Inclusion criteria

Inclusion criteria: Age >= 14 years; a cerebrospinal fluid cytological examination should be conducted for patients with suspected central nervous system infections who present with fever, headache, and altered mental status.

Exclusion criteria

Exclusion criteria: Pregnant women; Those diagnosed with central nervous system infections at other hospitals and receiving treatment; Confirmed cancer patients; Patients with traumatic brain injury who have undergone craniotomy and are suspected of having central nervous system infections; Those who have incomplete data within 24 hours of admission, making scoring and information collection impossible.

Design outcomes

Primary

MeasureTime frame
Cerebrospinal fluid pressure (primary, end), cerebrospinal fluid appearance, color, protein, glucose, cell number, lactate;28-day mortality rate;ICU occupancy rate;Total length of hospital stay;ICU Stay Days;

Secondary

MeasureTime frame
General information: gender, age, onset time;Vital signs: body temperature, heart rate, respiration, systolic blood pressure, diastolic blood pressure, peripheral oxygen saturation, state of consciousness (GSC score);

Countries

China

Contacts

Public ContactShichao Lai

West China Hospital of Sichuan University

lsc217@scu.edu.cn+86 159 8237 2698

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026