neuromyelitis optica spectrum disorder
Conditions
Interventions
NMOSD with PTS group/ NMOSD without PTS group:None
Sponsors
Shanghai Jing'an District Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.NMOSD patients who meet the 2015 version of the Wingerchuk diagnostic criteria; 2.NMOSD patients with LETM onset for the first time; 3.The vital signs are stable; 4.Voluntarily participate in this experiment and sign the informed consent;
Exclusion criteria
Exclusion criteria: 1.Patients with epilepsy, trauma, tumors, etc., which affect the judgment of the disease; 2.Incomplete medical records; 3.Consciousness disturbance, severe cognitive or/and speech dysfunction, unable to complete the assessment; 4.Those with metal implants or other contraindications to MRI scanning; 5.Those who do not cooperate with the inspection and do not sign the informed consent;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Penn Spasm Frequency Scale;Numerical Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| American Spinal Injury Association Impairment Scale, AIS;clinical symptoms;physical examination;blood tests;cerebrospinal fluid tests;Multimodal spinal magnetic image resonance;Demographic data;AQP4 antibody;extended disability status scale, EDSS;Berg balance scale, BBS;Barthel Index, BI;short-form 36 item health survey questionnaire, SF-36; | — |
Countries
China
Contacts
Public ContactQinying Li
Shanghai Jing'an District Central Hospital
Outcome results
None listed