Stroke
Conditions
Interventions
Experimental Group:Conventional drug + transcranial alternating current stimulation
Control group:Conventional drug + sham stimulation
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Ischemic stroke confirmed by CT/MRI; (2) Aged >=30 years and =3 months and <=1 year, unilateral hemiplegia; (5) Cognitive impairment, Montreal Cognitive Assessment (MoCA) <26 points.
Exclusion criteria
Exclusion criteria: (1) Patients with contraindications to MRI, such as pacemakers, heart stents, claustrophobia, etc. (2) Patients who have participated in or are currently participating in other clinical projects one month before enrollment; (3) Patients with contraindications to transcranial electrical stimulation, such as cochlear implants, history of epilepsy, and metal implants in the body; (4) Pregnant or lactating women; (5) Patients with severe mental illness, such as depression, schizophrenia, etc.; (6) Patients who are taking drugs that change the excitability of the cerebral cortex.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA); | — |
Secondary
| Measure | Time frame |
|---|---|
| auditory verbal learning test,AVLT;Shape Trail Test;Stroop test;Symbol Digit Modalities Test,SDMT;Boston Naming Test,BNT;verbal fluency test,VFT;Amplitude of Low Frequency Fluctuation,ALFF;Regional Homogeneity,ReHo;Functional Connectivity,FC;EEG;MRI; | — |
Countries
China
Contacts
Public ContactXue Xin
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed