Burning mouth syndrome
Conditions
Interventions
Burning mouth syndrome patient group:None
Healthy control group:None
Sponsors
College & Hospital of Stomatology, Guangxi Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the BMS group: patients experiencing the symptoms of oral burning recurring daily for >2h per day for >3 months without clinically evident causative lesions; patients aged between 40 and 80; patients with normal blood test findings (including blood count, liver and kidney functions, blood glucose levels and glycated hemoglobin, thyroid function, vitamin B12, serum ferritin and folic acid); patients understanding the questionnaire and participating voluntarily. Health group: healthy controls with the normal oral mucosa; healthy controls with age, gender, body mass index (BMI) and education level were basically matched with BMS patients.
Exclusion criteria
Exclusion criteria: Exclusion criteria for the BMS group: patients with a history of mental disorder or neurological or organic brain dysfunction, obstructive sleep apnoa syndrome, severe and uncontrolled systemic disease, or malignancy; patients undergoing the treatment with psychotropic drugs, or having used immunosuppressants in the last 3 months or antibiotics in the last 1 month; patients with a history of alcohol, smoking or drug abuse; patients with periodontitis, oral candidiasis and other oral mucosal diseases or inflammation. Exclusion criteria for the healthy group were similar to those for the BMS group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function;Biomarkers (Proteomics, Microbiome); | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety/Depression;Sleep index; | — |
Countries
China
Contacts
Public ContactXiaojie Lin
College & Hospital of Stomatology, Guangxi Medical University
Outcome results
None listed