enal anemia
Conditions
Interventions
Group one:LFHD+rhEPO
Group two:HFHD+rhEPO
Group three:HFHD+HIF-PHI
Sponsors
Rongchang District People's Hospital of Chongqing
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Diagnosis: Chronic renal failure, uremia (CKD stage 5). Diagnostic criteria: Creatinine clearance rate = 707 umol/L, with dialysis frequency of no less than 3 times per week (2020 KDIGO guidelines). 2.Meet the criteria for anti-anemia treatment in dialysis patients: Hemoglobin < 100g/L. 3.The medical record data is complete, and regular hemodialysis treatment has been carried out in our hospital for more than 3 months.
Exclusion criteria
Exclusion criteria: (1) Patients who received treatments for increasing HB within one month. (2) Patients who used hormones or cytotoxic drugs within the recent three months. (3) Patients who had a history of blood transfusion or intravenous use of iron supplements within three months. (4) Patients with chronic bleeding. (5) Severe malnutrition, liver insufficiency, heart failure, gastric ulcer or blood disorders. (6) Dialysis time is less than three months or the patient cannot adhere to regular hemodialysis. (7) The patient is not voluntarily participating in this study, or withdraws due to changes in condition, death or personal request during the study.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Hematocrit;serum ferritin;total iron-binding capacity;Transferrin saturation; | — |
Primary
| Measure | Time frame |
|---|---|
| hemoglobin; | — |
Countries
China
Contacts
Public ContactGuo Jiguang
Rongchang District People's Hospital of Chongqing
Outcome results
None listed