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A Randomized Controlled Clinical Study on the Effects of Different Ventilation Modes on CLCVP, Blood Loss, and Postoperative Recovery in Patients Undergoing Laparoscopic Liver Resection

A Randomized Controlled Clinical Study on the Effects of Different Ventilation Modes on CLCVP, Blood Loss, and Postoperative Recovery in Patients Undergoing Laparoscopic Liver Resection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095153
Enrollment
Unknown
Registered
2025-01-02
Start date
2023-04-13
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cancer

Interventions

Volume control ventilation group:In the volume group, controlled ventilation was performed during the operation, and relevant observation indexes and postoperative follow-up indexes were recorded
Pressure control volume guaranteed ventilation group:In the pressure control ventilation group, pressure control and volume ventilation were implemented during the operation, and relevant observation

Sponsors

Guangdong Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Gender unrestricted, age 18-80 years; 2. ASA I-III, without severe systemic disease; 3. BMI: 18.5-30 kg/m^2; 4. Child-Pugh classification: Grade A; 5. Voluntarily participating in the study and signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Severe hypertension, diabetes, coronary artery disease, arrhythmias, cerebrovascular diseases; severe impairment of liver, kidney, or lung function; 2. Cancer with extensive metastasis; 3. Autoimmune diseases; 4. Pregnant, menstruating, or lactating women; 5. Presence of mental disorders or difficulty in communication; 6. Patients or their family members who refuse to participate.

Design outcomes

Primary

MeasureTime frame
Intraoperative blood loss;

Secondary

MeasureTime frame
Postoperative recovery quality;Intraoperative respiratory parameters;Postoperative Numerical Pain Score (NRS);Dosage of anesthetic drugs for operation;Cardiovascular drug dosage and intraoperative monitoring indexes;Postoperative hospital stay;Complications 30 and 90 days after surgery;

Countries

China

Contacts

Public ContactMin Zhong

Guangdong Hospital of Traditional Chinese Medicine

304637372@qq.com+86 137 1001 1776

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026