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Effect of distal limb ischemic preconditioning on postoperative gastrointestinal function recovery in patients undergoing laparoscopic surgery

Effect of distal limb ischemic preconditioning on postoperative gastrointestinal function recovery in patients undergoing laparoscopic surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095141
Enrollment
Unknown
Registered
2025-01-02
Start date
2025-01-06
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative gastrointestinal dysfunction

Interventions

Strengthen intervention group:Interrupt blood flow with a tourniquet for 5 minutes on the day before surgery and before induction, for a total of 3 times for ischemic preconditioning
Intervention group:Interrupt blood flow with a tourniquet for 5 minutes before induction, for a total of 3 times for ischemic preconditioning
Control group :Apply pressure of 60mmHg without blocking blood flow before induction

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Patients scheduled for laparoscopic non gastrointestinal surgery; 2) The operation time was > 1h, < 4h; 3) 18 years old <= Age <= 60 years old; 4) BMI 18.5~30 kg/m2; 5) ASA I-III; 6) Mentally normal, with certain understanding and communication skills;

Exclusion criteria

Exclusion criteria: 1) History of major abdominal surgery and gastrointestinal diseases in the past; 2) History of allergy to analgesics or drug addiction; 3) Suffering from blood diseases such as hemophilia and thrombocytopenic purpura, as well as vascular diseases such as lower limb thrombosis, varicose veins, and severe arteriosclerosis; 4) Preoperative severe cardiovascular and cerebrovascular diseases or abnormal liver and kidney function; 5) Combination of other active infections upon admission or any other inflammation and medical complications during hospitalization; 6) Pregnant and lactating patients; 7) Patients undergoing emergency trauma surgery; 8) Patients participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
time of first postoperative exhaust time;

Secondary

MeasureTime frame
Nausea and vomiting score;VAS;Gastrointestinal function score;Percentage of lymphocytes;

Countries

China

Contacts

Public ContactWen Shen

Affiliated Hospital of Xuzhou Medical University

shenwen670201@163.com+86 180 5226 8689

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 8, 2026