Post-stroke cognitive impairment
Conditions
Interventions
The Treatment Group:The intervention group underwent transcranial alternating current stimulation (tACS) stimulation, routine internal medical treatment, and conventional rehabilitation functional tra
The Control Group:The intervention group underwent sham stimulation, routine internal medical treatment, and conventional rehabilitation functional training.
Sponsors
The Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age between 35 and 80 years old; 2. First occurrence of cerebral stroke (hemorrhagic/ ischemic) with a duration of 2 weeks to 6 months; 3. Diagnosis conforms to the diagnostic criteria of post-stroke cognitive impairment outlined in the "Expert Consensus on the Management of Post-Stroke Cognitive Impairment 2021"; 4. MoCA (Montreal Cognitive Assessment) scores: <=13 for illiterate individuals, <=19 for 1-6 years of education, <=24 for 7 years of education and above; 5. No metallic implants or pacemakers in the body; 6. Capable of understanding and cooperating with the rehabilitation assessment and treatment involved in this study; 7. Informed consent form to be signed by the patient or their immediate family member.
Exclusion criteria
Exclusion criteria: 1. Patients with cognitive impairment caused by other conditions such as brain tumors, senile dementia, hypothyroidism, or traumatic brain injury; 2. Individuals with residual effects from lacunar infarctions in the past; 3. Individuals or families with a history of epilepsy or mental illness; 4. Those with consciousness disorders, severe visual, auditory, or speech impairments; 5. Patients with fever, electrolyte imbalances, or unstable vital signs; 6. Individuals with severe dysfunction in vital organs such as heart, lungs, liver, or kidneys; 7. Patients with contraindications to tDCS, such as local skin injuries or inflammation, skull defects, or those with tactile hypersensitivity in the stimulation area.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment(MoCA);Trail Making Test A/B(TMT); | — |
Secondary
| Measure | Time frame |
|---|---|
| Digit Span Test;Rey-Osterrieth Complex Figure Test (ROCF);Resting-State Electroencephalography (EEG);The latency and amplitude of event-related potential P300; | — |
Countries
China
Contacts
Public ContactKong Weicheng, Xue Xiehua
The Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine
Outcome results
None listed