None
Conditions
Interventions
Group A:Subjects will first receive "bilateral transcranial magnetic stimulation targeting the left cerebellum combined with the right cerebral pharyngeal cortex", followed by "bilateral transcranial
Group B:The trial sequence for the subjects is as follows: "Right cerebellum combined with left cerebral pharyngeal cortex dual-target transcranial magnetic stimulation," followed by "Cerebellar vermi
Group C:The subjects first undergo "Cerebellar vermis combined with either cerebral pharyngeal cortex dual-target transcranial magnetic stimulation," followed by "Left cerebellum combined with right c
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age>=30 years old and <=60 years old, gender is not limited; 2. Normal speech and swallowing function, no choking when drinking or eating; 3. Voluntarily sign the informed consent form after a comprehensive understanding of the research protocol and potential risks.
Exclusion criteria
Exclusion criteria: 1. Patients with a clear history of hypertension and no effective blood pressure control by medication, or patients with severe cardiovascular, hepatic, renal, blood, digestive or respiratory diseases, including patients with mental illness, malignant tumors, patients with venous thrombosis, osteoporosis, severe bleeding tendency or neck infection; 2. Pregnant and lactating women or those who plan to get pregnant in the near future; 3. Previous or current cerebral infarction, cerebral hemorrhage, cerebral atrophy, Parkinson's disease, Alzheimer's disease and other central nervous system diseases; 4. Have a history of epilepsy or a family history of epilepsy; 5. Those who have participated in or are participating in other clinical trials within 3 months; 6. There are contraindications to electromyography examination, such as patients with bleeding tendency, cardiac pacemaker or cardioversion equipment, and those who are susceptible to recurrent and systemic infections; 7. There are contraindications to enhanced CT, such as patients with allergy to iodine drugs, hyperthyroidism, patients with severe renal insufficiency, and diabetic patients taking biguanide preparations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amplitude of the motor evoked potential of the cricopharyngeal muscle.;The latency of the motor evoked potential of the cricopharyngeal muscle.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of EMG activity of suprahyoid/submental muscles;Duration of laryngopharyngeal mechanogram;Duration of the inhibition of the CP muscle EMG activity; Interval between onset of EMG activity of suprahyoid/submental muscles and onset of laryngopharyngeal mechanogram; | — |
Countries
China
Contacts
Public ContactWan Ping
School of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed