Postherpetic neuralgia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The diagnosis of neuropathic pain conforms to the criteria of the 2013 Expert Consensus on the Diagnosis and Treatment of Neuropathic Pain. (2) Age 18~60 years old. (3) Hamilton Anxiety Scale 14-item (HAMA?14) score >= 7 points and/or Hamilton Depression Rating Scale 17 items (HAMD?17) score of >=8 points, and Pain Numeric Evaluation Scale (NRS) score >= 4 points.
Exclusion criteria
Exclusion criteria: (1) Contraindications to repetitive transcranial magnetic stimulation such as epilepsy, intracranial metal implants, and pregnancy. (2) Combined with intracranial organic lesions or craniocerebral trauma. (3) Are taking drugs such as naloxone that interfere with the analgesic effect of repetitive transcranial electrical stimulation. (4) Acute pain caused by gout, trauma or post-operative pain. (5) Anxiety and depressive mood disorder before the onset of neuropathic pain. (6) Mood disorders such as anxiety and depression caused by other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Health Questionnaire-9;Generalized Anxiety Disorder-7;Heart Rate Variability;Pittsburgh sleep quality index; | — |
Countries
China
Contacts
Huadong Hospital, Fudan University