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Efficacy Study of Transcranial Temporal Interference Electrical Stimulation (TI) on Patients with Postherpetic Neuralgia

Research on the Treatment of Neuropathic Pain with Non-invasive Deep Brain Stimulation Technology (TI)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095096
Enrollment
Unknown
Registered
2025-01-01
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postherpetic neuralgia

Interventions

Tl group:The experimental group used TI electrical stimulation + conventional therapy
Sham stimulation group:The sham stimulation group was treated with Ti sham stimulation + conventional therapy

Sponsors

Huadong Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) The diagnosis of neuropathic pain conforms to the criteria of the 2013 Expert Consensus on the Diagnosis and Treatment of Neuropathic Pain.  (2) Age 18~60 years old. (3) Hamilton Anxiety Scale 14-item (HAMA?14) score >= 7 points and/or Hamilton Depression Rating Scale 17 items (HAMD?17) score of >=8 points, and Pain Numeric Evaluation Scale (NRS) score >= 4 points.

Exclusion criteria

Exclusion criteria: (1) Contraindications to repetitive transcranial magnetic stimulation such as epilepsy, intracranial metal implants, and pregnancy. (2) Combined with intracranial organic lesions or craniocerebral trauma. (3) Are taking drugs such as naloxone that interfere with the analgesic effect of repetitive transcranial electrical stimulation. (4) Acute pain caused by gout, trauma or post-operative pain.  (5) Anxiety and depressive mood disorder before the onset of neuropathic pain. (6) Mood disorders such as anxiety and depression caused by other reasons.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;

Secondary

MeasureTime frame
Patient Health Questionnaire-9;Generalized Anxiety Disorder-7;Heart Rate Variability;Pittsburgh sleep quality index;

Countries

China

Contacts

Public ContactZheng Yongjun

Huadong Hospital, Fudan University

Zhengyongjun1971@126.com+86 181 1626 7895

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026