Obesity
Conditions
Interventions
Group O (Obesity Group):According to BMI classification, those with a BMI < 40 kg/m2 are included in this group
Group OB (Morbid Obesity Group):According to BMI classification, those with a BMI =40 kg/m2 are included in this group
Sponsors
Zhengzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age 18 to 35 years; 2.ASA classification of 1 to 3; 3.patient informed consent;
Exclusion criteria
Exclusion criteria: 1.Severe alcohol abuse or history of substance abuse; 2.moderate to severe obstructive sleep apnea requiring non-invasive ventilatory support during the perioperative period; 3.presence of severe cardiovascular disease; 4.history of liver or kidney dysfunction; 5.presence of neuromuscular diseases;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brief Pain Assessment Scale (BPI) score at 24 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| pain threshold;pain tolerance;Levels of TNF-a, IL-1ß, IL-6, IL-8, and IL-10;Postoperative analgesia satisfaction;Patient recovery quality score (QOR-15) at 24 h and 48 h after surgery; | — |
Countries
China
Contacts
Public ContactYan Wang
Zhengzhou Central Hospital
Outcome results
None listed