Obstructive Sleep Apnea-Hypopnea Syndrome
Conditions
Interventions
Cyclopofol group:Anesthesia induction: intravenous cyclopofol
Anesthesia maintenance: Pump cyclopofol
Propofol group:Anesthesia induction: intravenous injection of propofol
Anesthesia maintenance: pump propofol
Remimazolam group:Anesthesia induction: intravenous remimazolam
Anesthesia maintenance: Pump remimazolam
Sponsors
Lu 'an Hospital Affiliated to Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: ASAI-III, male or female, age 18~64 years old, OSAHS patients who undergo elective UPPP surgery in our hospital.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to the study drug; 2. People with schizophrenia and severe depressive state. 3. Myasthenia gravis; 4. Patients with respiratory diseases (asthma, airway hyperresponsiveness, acute exacerbation of chronic obstructive pulmonary disease); 5. Patients with cardiovascular diseases (acute myocardial infarction, heart failure, severe arrhythmia and atrioventricular block, etc.); 6. Patients with other serious systemic diseases; 7. Those with severe obesity and BMI >=35.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tracheal intubation stress reaction;Emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative cognitive dysfunction;Intraoperative awareness;Injection pain;Postoperative nausea and vomiting; | — |
Countries
China
Contacts
Public ContactRenhu Li
Lu 'an Hospital Affiliated to Anhui Medical University
Outcome results
None listed