Gallbladder Disorders
Conditions
Interventions
General anesthesia group (GA):Simple general anesthesia group
Superior arcuate ligament quadrate block group (QG group):Before general anesthesia (0.375% ropivacaine 20ml on both sides)ultrasound-guided block of the quadrate lumbus muscle of the superior arcuate
Dexmedetomidine combined with ropivacaine for superior arcuate ligament quadrate block group (DQG group):Before general anesthesia (0.375% ropivacaine combined with 0.1ug/kg dexmedetomidine 20ml on bo
Sponsors
Panzhihua Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years old, American Society of Anesthesiologists (ASA) grade I.-II; 2. Laparoscopic cholecystectomy under general anesthesia; 3. Body mass index (BMI) 18-28kg/m^2; 4. Patients who are able to understand and are willing to report pain using the VAS score.
Exclusion criteria
Exclusion criteria: 1. Recent use of anticoagulant medications; 2. Allergy to the drugs used in the anesthesia process; 3. Severe cardiovascular and hematologic diseases; 4. Long-term use of opioids, sedatives, antidepressants, monoamine oxidase inhibitors and other drugs; 5. Myasthenia gravis, Parkinson's disease, or pregnancy; 6. History of previous thoracic or spinal surgery; 7. Preoperative cognitive impairment and inability to cooperate with pain assessment; 8. Local infection or systemic infection at the puncture site; 9. Failure to complete intraoperative data collection and postoperative follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog Scale scores ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of heart rate and mean arterial pressure after entering the operating room (T0), after nerve block (T1), intubation time (T2), incision time (T3), after surgery (T4), and extubation time (T5);Operation time;Duration of anesthesia;Intraoperative opioid consumption;The time of the first significant pain after surgery;Time, type and dose of postoperative rescue analgesics and antiemetic drugs;Adverse reaction;Ramsay sedation evaluation;Satisfaction rating;First time out of bed activity;Length of stay; | — |
Countries
China
Contacts
Public ContactZhu Taifang
Panzhihua Central Hospital
Outcome results
None listed