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Study on the safety and effectiveness of open decompression of mental foramen combined with nerve repair membrane in relieving postoperative sensory disturbance of mental nerve

Study on the safety and effectiveness of open decompression of mental foramen combined with nerve repair membrane in relieving postoperative sensory disturbance of mental nerve

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400095038
Enrollment
Unknown
Registered
2024-12-31
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The swelling of the mental nerve was followed by local compression, resulting in decreased sensory function of the mental nerve.

Interventions

Experimental group:Open mental foramen

Sponsors

Hospital of Stomatology Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Preoperative CBCT identified that the surgical area is adjacent to the mental foramen; 2.Ages between 18 and 60; 3.No history of drug or food allergy; 4.No mental illness; No serious cardiovascular and cerebrovascular history; There was no history of trigeminal neuralgia and no numbness of bilateral lower lip before surgery. There were no other potential factors in the oral cavity that may cause inferior alveolar nerve/mental nerve injury before surgery, including tumor, trauma, inflammation, etc; 5.Patients who are willing to participate in this trial and sign informed consent;

Exclusion criteria

Exclusion criteria: 1.Patients with disruption of mental nerve continuity; 2.Patients with infectious inflammation at the surgical site; 3.Patients have uncontrolled diseases such as diabetes, chondrosis, thyroid disease, and severe liver and kidney dysfunction; 4.Patients with long-term adrenal corticosteroid therapy; 5.Patients with autoimmune diseases; 6.Patients undergoing radiation therapy; 7.Patients with severe smoking habits; 8.Patients with clinical diagnosis of mental anxiety and hypersensitivity; 9.Patients who did not wish to participate in the trial, or who were deemed unsuitable by the investigators;

Design outcomes

Primary

MeasureTime frame
Intraoperative lower lip numbness;

Countries

China

Contacts

Public ContactNancy

Hospital of Stomatology Wuhan University

jnwang@whu.edu.cn+86 27 87686386

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026