hypertensive disorder complicating pregnancy
Conditions
Interventions
Tight control:NA
Loose control:NA
Sponsors
Shanghai First Maternity and Infant Health Hospital (Tongji University Affiliated Obstetrics and Gynecology Hospital)
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: The presence of elevated blood pressure at 14 weeks 0 days to 33 weeks 6 days of gestation, office diastolic blood pressure of 90 to 105 mmHg (85 to 105 mmHg if taking antihypertensive drugs).
Exclusion criteria
Exclusion criteria: Systolic blood pressure =160 mmHg (subsequent inclusion if systolic blood pressure < 160 mmHg after treatment and all other eligibility criteria are met), diagnosis of proteinuria, use of angiotensin-converting enzyme (ACE) inhibitors at 14 weeks 0 days of gestation and beyond, preconception diabetes or kidney disease, need for delivery due to maternal or fetal reasons, multiple pregnancies, The fetus has a severe abnormality or chromosomal abnormality, has a plan to terminate the pregnancy, and has participated in CHIPS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite primary outcomes include pregnancy loss (miscarriage, ectopic pregnancy, pregnancy termination, stillbirth, or neonatal death) or the need for a high level of neonatal care for more than 48 hours within 28 days of birth; | — |
Secondary
| Measure | Time frame |
|---|---|
| eclampsia;HELLP syndromne;placental abruption;intra uterine fetal death;fetal growth restriction;neonatal septicemia; | — |
Countries
China
Contacts
Public ContactXiaolin Hua
Shanghai First Maternity and Infant Health Hospital (Tongji University Affiliated Obstetrics and Gynecology Hospital)
Outcome results
None listed