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A time,motion and cost assessment study of a subcutaneous (SC) pertuzumab and trastuzumab fixed-dose combination (PH FDC) for the treatment of HER2-positive early breast cancer (HER2+ EBC)

A time,motion and cost assessment study of a subcutaneous (SC) pertuzumab and trastuzumab fixed-dose combination (PH FDC) for the treatment of HER2-positive early breast cancer (HER2+ EBC)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400095009
Enrollment
Unknown
Registered
2024-12-31
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

PH-FDC-SC group:no
P-IV+H-IV group:None
P-IV + H-SC group:None

Sponsors

Cancer Hospital Affiliated to Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1)Agree to participate in the study and sign the informed consent form; 2)Female patients with breast cancer aged >=18 years; 3)Pathological molecular typing is HER2 +; 4)Complete tumor clinical pathology information; 5)Patients who received subcutaneous or intravenous PH injections from 7th to 18th after receiving combination chemotherapy (to ensure that any deviations from IV and SC dosing were similar).

Exclusion criteria

Exclusion criteria: 1)History of previous treatment for other malignancies; 2)Incomplete tumor clinical pathology information.

Design outcomes

Primary

MeasureTime frame
Time savings for HCP with PH-FDC-SC vs P-IV+H-IV and P-IV+H-SC in the adjuvant treatment of HER2-positive EBC patients;

Secondary

MeasureTime frame
Time savings for patients with PH-FDC-SC vs P-IV+H-IV and P-IV+H-SC in the adjuvant treatment of HER2-positive EBC .;Consumption usage and cost of drug waste;

Countries

China

Contacts

Public ContactMeng Yingtao

Cancer Hospital Affiliated to Shandong First Medical University

187251135@qq.com+86 186 1520 3603

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026