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Clinical observation of intravenous lidocaine on postoperative nausea and vomiting in female patients undergoing thoracoscopic radical resection for lung cancer

Clinical observation of intravenous lidocaine on postoperative nausea and vomiting in female patients undergoing thoracoscopic radical resection for lung cancer

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400095006
Enrollment
Unknown
Registered
2024-12-31
Start date
2025-02-05
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer with nausea and vomiting

Interventions

Experimental group: Lidocaine group (Group A):Lidocaine was injected intravenously at 1.5mg/kg during anesthesia induction and pumped continuously at 2mg/kg/h during the operation until 5 minutes befo
Control group: Normal saline group (Group B):During anesthesia induction, saline with the same ml of lidocaine as the experimental group was injected intravenously, and saline with the same ML of lido

Sponsors

Chinese People's Liberation Army Western Theater Command General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective thoracoscopic radical lung cancer surgery under general anesthesia were anesthetized 2. Female, ages 18-65 3. The method was intravenous general anesthesia 4.ASA grade I-III

Exclusion criteria

Exclusion criteria: 1. Patients with lidocaine allergy and contraindications 2. Previous thoracic surgery history 3. Use opioids, antiemetics, or corticosteroids within 24 hours before surgery 4. Preoperative radiotherapy and chemotherapy were performed 5. Serious cardiovascular and cerebrovascular diseases 6. Severe liver and kidney dysfunction 7. Complicated with mental illness 8. Uncooperative or unable to communicate with patients to complete postoperative follow-up

Design outcomes

Primary

MeasureTime frame
Nausea and vomiting;Pain score;Postoperative recovery quality;

Countries

China

Contacts

Public ContactYang Haihong

Chinese People's Liberation Army Western Theater Command General Hospital

zzumazui@sina.com+86 181 8097 3282

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026