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New Glucose Monitoring Indicators TIR , TBR , and TAR , and Their Impact on Cognitive Function in Older Patients with Type 2Diabetes

New Glucose Monitoring Indicators TIR , TBR , and TAR , and Their Impact on Cognitive Function in Older Patients with Type 2Diabetes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094996
Enrollment
Unknown
Registered
2024-12-31
Start date
2023-04-17
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Project fund

Interventions

Low TIR group: TIR 70%:None

Sponsors

Jinan First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. The disease course of T2DM was > 1 year and the patients were over 60 years old. All patients met the WHO diagnostic criteria for diabetes in 1999; 2. Continuous blood glucose monitoring by CGM system with complete case data; 3. All the patients underwent functional magnetic resonance imaging (FMRI).

Exclusion criteria

Exclusion criteria: 1. Serious complications of diabetes; 2. History of stroke, Parkinson's disease, epilepsy, major depression, and other neurological or psychiatric disorders; 3. History of head trauma or brain space occupying disease; 4. Patients with contraindications for MRI examination; 5. Brain MRI routine sequence scan for patients with organic brain lesions

Design outcomes

Primary

MeasureTime frame
Regional Homogeneity,ALFF;Functional connectivity,FC;fractional ALFF,fALFF;Regional Homogeneity, ReHo;—

Countries

China

Contacts

Public ContactLi Liyan

Jinan First People's Hospital

shashuang2513@163.com+86 150 5414 2339

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026