Nasopharyngeal carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with nasopharyngeal carcinoma diagnostic criteria for nasopharyngeal carcinoma who are newly diagnosed with biopsy and meet the definition of stage III and IV in the AJCC 8th edition nasopharyngeal carcinoma staging system; and has not undergone any chemoradiotherapy and surgery for nasopharyngeal carcinoma; Induction chemotherapy was received, and MRI was performed after the induction chemotherapy was completed to evaluate the tumor response.
Exclusion criteria
Exclusion criteria: Have a history of other cancers; Those who have contraindications such as claustrophobia or a history of metal implantation and cannot complete the MRI examination; poor MRI image quality (e.g., motion artifacts); The MRI image of the tumor is unclear and cannot be measured; Tumors that are too small can affect the diagnosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor regression or progression rates before and after chemotherapy;Differences between C/W values in MRE;AUC value; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hardness C value, fluidity W value;T1 value, ADC value, and DCE-MRI enhancement curve; | — |
Countries
China
Contacts
People's Hospital of Guangxi Zhuang Autonomous Region