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A cohort study on the efficacy and changes in bone metabolism-related indicators of Anovel regimen in HIV-1 positive treated patients

A cohort study on the efficacy and changes in bone metabolism-related indicators of Anovel regimen in HIV-1 positive treated patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094987
Enrollment
Unknown
Registered
2024-12-31
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AIDS

Interventions

Observation group:None

Sponsors

Liuzhou people's hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age>=18 years; 2. Meet the diagnostic criteria for HIV/AIDS in the Chinese Guidelines for the Diagnosis and Treatment of AIDS (2024 Edition); 3. Have been treated with HAART (Highly active antiretroviral therapy) for more than 1 year, and have confirmed virologic suppression (HIV RNA<20 cpm) twice; 4. Have certain reading and writing ability, voluntarily sign the informed consent form, and be willing to cooperate with this study.

Exclusion criteria

Exclusion criteria: 1.Patients who have recently or are currently taking corticosteroids, calcium supplements, or anti-osteoporosis medications; 2.Patients with rheumatic immune-related diseases; 3.Patients with severe liver or kidney dysfunction; 4.Patients with malignant tumors: bone tumors, leukemia, etc; 5.Patients with other endocrine system diseases; 6.Patients with renal osteodystrophy due to nephrotic syndrome; 7.Patients with poor compliance or who are unable to participate in regular check-ups; 8.Pregnant and lactating women; 9.Those whom the researcher deems unsuitable for participation in this study project.

Design outcomes

Primary

MeasureTime frame
HIVRNA;Bone mineral density;Rate of virological inhibition;

Secondary

MeasureTime frame
Cumulative discontinuation rate due to AEs;

Countries

China

Contacts

Public ContactZhang Peng

Liuzhou people's hospital

aze0916@aliyun.com+86 772 2662857

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026