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A prospective single-center study of fluorescence surgical navigation for liver cancer based on near-infrared fluorescent probe (B7H3-IRDye800CW)

A prospective single-center study of fluorescence surgical navigation for liver cancer based on near-infrared fluorescent probe (B7H3-IRDye800CW)

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094983
Enrollment
Unknown
Registered
2024-12-31
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cancer

Interventions

Experimental Group:B7H3-IRDye800CW

Sponsors

Dazhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Patients who meet the criteria of the "Primary Liver Cancer Diagnosis and Treatment Guidelines (2019 Edition)" and are clinically diagnosed with primary liver cancer; 2) Patients who are clinically diagnosed with primary liver cancer and are ready for open liver cancer surgery (including radical resection and tumor reduction) based on preoperative imaging and laboratory tests. Patients who are not suitable for surgery or who are unwilling to undergo laparoscopic liver cancer resection; 3) Child-Pugh A liver function; 4) Aged 18 to 80 years old, regardless of gender; 5) Voluntary signing of informed consent.

Exclusion criteria

Exclusion criteria: 1) Patients who have used ICG or other fluorescent dyes; 2) Patients who are allergic to iodine; 3) Patients who have participated in other clinical trials within 3 months; 4) Patients who are considered unsuitable for inclusion by the researchers; 5) Patients whose systemic and organ conditions are considered to be difficult to tolerate liver cancer resection due to preoperative evaluation; 6) Patients or guardians who are unwilling or unable to provide written informed consent or do not comply with follow-up requirements.

Design outcomes

Primary

MeasureTime frame
operation time;The bleeding;Rate of R0 cut edge;progression-free survival;Overall Survival;

Secondary

MeasureTime frame
Postoperative ALT and AST levels;Hospital stays;Hospital costs;Incidence of adverse events;

Countries

China

Contacts

Public ContactJie Liu

Dazhou Central Hospital, Dazhou City, Sichuan Province

1099655204@qq.com+86 152 2847 3971

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026