Knee Joint Ankylosis
Conditions
Interventions
Control group:None
Experimental Group:None
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Diagnosis: Subjects clinically diagnosed with knee flexion less than 90 degrees, meeting the definition of severe knee contracture; 2) Subjects with no significant changes in knee range of motion within the last 3 months; 3) Imaging shows non-ossified stiffness in the subjects; 4) Good and elastic skin and soft tissue around the knee joint; 5) Inpatients, both male and female, aged 18-65, who voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Subjects with knee joint stiffness undergoing adhesion release due to other specific reasons such as infection or history of infection, patellofemoral bony fusion, patellar deformity, ligament reconstruction, as per international consensus; 2) Presence of other systemic diseases such as malignancies, hematologic disorders, rheumatic and endocrine metabolic diseases; 3) Minors under 18 years of age, pregnant and lactating women; 4) History of drug and alcohol abuse, cognitive impairment, or psychiatric disorders; 5) Any other conditions deemed unsuitable for inclusion by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quadriceps Index Change Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| RNA gene expression in skeletal muscle;Active/Passive Range of Motion;Change Rate of Distal Quadriceps Volume;Bilateral Lower Limb Symmetry Index;P4 Pain Score;Tegner Score;IKDC Score;KOOS Score;AKSS Score;Lysholm Score;36-Item Short Form Survey; | — |
Countries
China
Contacts
Public ContactZhao Jinzhong
Shanghai Sixth People's Hospital
Outcome results
None listed