Post-traumatic stress disorder
Conditions
Interventions
The Etomidate Group :None
Sponsors
Hebei Medical University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Patients with life-threatening trauma requiring emergency surgery; 2.The method of anesthesia was intravenous general anesthesia, and induction drugs included propofol or etomidate; 3.Aged from 18 to 60, regardless of gender; 4.Informed consent has been obtained from the patient.
Exclusion criteria
Exclusion criteria: 1.With a history of traumatic brain injury and brain disease; 2.Cognitive impairment, defined as a simple mental state examination (MMSE) score < 24; 3.Neurological or psychiatric history; 4.Long-term use of sedative, psychotropic, anticholinergic drugs; 5.A history of alcohol or drug dependenc; 6.Severe visual, hearing, or speech impairment; 7.Liver and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Injury severity score;The time between the injury and the onset of anesthesia;Acute physiological and chronic health scores;Mini-Mental State Examination;Glasgow Coma Scale;Medication during Surgery;Double frequency index of heart rate, blood pressure and EEG before and after induction;Post-traumatic Stress Disorder Checklist-Civilian Version;Beck Depression Inventory;Beck Anxiety Inventory;Visual analogue scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Health-related quality of life score;Post-anesthesia complication;30-day postoperative mortality; | — |
Countries
China
Contacts
Public ContactWang Qiujun
Hebei Medical University Third Hospital
Outcome results
None listed