Depressive disorders
Conditions
Interventions
Depression Disorder Group:None
Normal Control Group:None
Sponsors
Hangzhou Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
12 Years to 15 Years
Inclusion criteria
Inclusion criteria: Depression Disorder Group: 1. Demographic criteria: Age: 12-15 years; Ethnicity: Han; Handedness: Right-handed; 2. Meets DSM-5 diagnostic criteria for depression disorder, with a total score of 17 or higher on the 17-item scale; 3. Has not taken any antipsychotic, antidepressant, or sedative/hypnotic medications in the past two weeks. Normal Control Group: 1. Demographic criteria: Age: 12-15 years; Ethnicity: Han; Handedness: Right-handed; 2. Has not previously taken any antipsychotic, antidepressant, or sedative/hypnotic medications; 3. Good social functioning (able to attend school normally, not retired due to illness).
Exclusion criteria
Exclusion criteria: Depression Disorder Group: 1. Individuals with severe physical illnesses or neurological disorders; 2. Meets any other mental disorder diagnostic criteria according to DSM-5; 3. Unable to effectively complete assessments: auditory or visual abnormalities, inability to cooperate with saliva collection, etc.; 4. Presence of contraindications for ACS treatment: scalp skin lesions, skull defects, presence of metallic implants in the brain, etc.; 5. Participant or guardian does not consent to participate in this study. Normal Control Group: 1. Individuals with severe physical illnesses or neurological disorders; 2. Meets any mental disorder diagnostic criteria according to DSM-5; 3. Unable to effectively complete assessments: auditory or visual abnormalities, inability to cooperate with saliva collection, etc.; 4. Presence of contraindications for tACS treatment: scalp skin lesions, skull defects, presence of metallic implants in the brain, etc.; 5. Participant or guardian does not consent to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demographic information;Growing experience;Test of Variables of Attention;Child Behavior Checklist;17-Hamilton Depression Scale;Piers-Harris Children’s Self-concept Scale;Wagnild-Young Resilience Scale;The Inventory of Parent and Peer Attachment;Short-form Egna Minnenav Barndoms Uppfostran;Raven's Standard Progressive Matrices;The 9 item Patient Health Questionnaire;The 7 item Generalized Anxiety Disorder;The 90 item self-report Symptom checklist;Parental Bonding Instrument;The Attachment Style Questionnaire;Parenting Stress Index-Short Form;Cambridge Neuropsychological Test Automatic Battery;Event-related potential;fNIRS; | — |
Countries
China
Contacts
Public ContactLi Xiaojing
Hangzhou Seventh People's Hospital
Outcome results
None listed