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Effect of perioperative analgesia on cognitive dysfunction after off-pump coronary artery bypass grafting

Effect of perioperative analgesia on cognitive dysfunction after off-pump coronary artery bypass grafting

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094954
Enrollment
Unknown
Registered
2024-12-31
Start date
2023-04-13
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive impairment

Interventions

Sham Group:None
POCD Group:None

Sponsors

Shandong Provincial Hospital Affiliated to Shandong First Medical University(Shandong Provincial Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients who meet the diagnostic criteria of coronary heart disease (CHD) and undergo OPCABG at selected time; 2.Over 60 years old; 3.Informed consent and ethical approval; 4.There was no cognitive impairment by MMSE before operation; 5.Postoperative cognitive dysfunction occurred.

Exclusion criteria

Exclusion criteria: Complicated with aortic plaque, carotid artery stenosis, history of stroke, history of cerebral ischemic attack, visual impairment, hearing impairment, severe alcoholism, drug dependence, mental system or other cognitive dysfunction.

Design outcomes

Primary

MeasureTime frame
Incidence of POCD;Pain level;—

Secondary

MeasureTime frame
General information (patient's age, sex, height, weight, BMI, ASA classification, anesthesia time and operation time);—

Countries

China

Contacts

Public ContactLi Wei

Shandong Provincial Hospital Affiliated to Shandong First Medical University(Shandong Provincial Hospital)

liweisl@sdfmu.edu.cn+86 187 5315 7679

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026