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Research on the Construction of an Intelligent Diagnostic and Early Warning Model for Severe Acute Pancreatitis Based on CT Artificial Intelligence Technology

Research on the Construction of an Intelligent Diagnostic and Early Warning Model for Severe Acute Pancreatitis Based on CT Artificial Intelligence Technology

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094952
Enrollment
Unknown
Registered
2024-12-31
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pancreatitis

Interventions

Gold Standard:Part One Gold Standard: Organ Failure The assessment of organ failure is conducted using the modified Marshall scoring system, which includes three organ systems (respiratory, cardiova
Index test:Oxygen partial pressure
Venous blood creatinine
Blood pressure
Infection
Sensitivity
Area Under the Receiver Operating Characteristic Curve

Sponsors

Shanghai Changhai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Part One: Patients included in the first part are all those who were diagnosed with Acute Pancreatitis (AP). These patients underwent Contrast-Enhanced Computed Tomography (CECT) within 48 hours of admission. The definition of AP is based on the Revised Atlanta International Consensus (RAC) from 2012. A diagnosis of AP is made if two out of the following three criteria are met: The patient presents with abdominal pain consistent with AP (persistent, severe, and often radiating to the back); Serum lipase or amylase levels are more than three times the upper limit of normal; Imaging findings consistent with AP on Contrast-Enhanced Computed Tomography (CECT), Magnetic Resonance Imaging (MRI), or Transabdominal Ultrasound. Part Two: The second part includes all patients who underwent percutaneous catheter drainage under CT guidance for "abdominal fluid collections" and had microbiological cultures. CT images were obtained before and after catheter placement for the drainage of these fluid collections.

Exclusion criteria

Exclusion criteria: Part 1: (1) Poor CT quality; (2) Incomplete items in the scanning period (non-contrast scan, arterial phase, portal phase, venous phase); (3) Has been diagnosed with chronic pancreatitis or history of recurrent pancreatitis; (4) History of primary pancreas (tumors, etc.); (5) Lack of corresponding laboratory indicators and clinical information. Part II: (1) Poor CT quality; (2) The drainage fluid is not cultured or there is no bacterial culture result.

Design outcomes

Primary

MeasureTime frame
Oxygen partial pressure;Venous blood creatinine;Blood pressure;Infection;Accuracy;Sensitivity;Specificity;Positive Predictive Value;Negative Predictive Value;Area Under the Receiver Operating Characteristic Curve;

Countries

China

Contacts

Public ContactYun Bian

Shanghai Changhai Hospital

bianyun2012@foxmail.com+86 138 1635 7024

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026