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The effect of ultrasound-guided rhomboid intercostal low serratus plane block on postoperative pain and immune cell function in patients undergoing laparoscopic radical nephrectomy

The effect of ultrasound-guided rhomboid intercostal low serratus plane block on postoperative pain and immune cell function in patients undergoing laparoscopic radical nephrectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094909
Enrollment
Unknown
Registered
2024-12-30
Start date
2025-01-10
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Interventions

R Group:General anesthesia combined with ultrasound-guided plane block of rhombus intercostal low serratus anterior muscle
C Group:Simple general anesthesia

Sponsors

The General Hospital of Western Theater Command
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) classification I-II 2. Age range of 18-65 years old, body mass index (BMI) 18-24kg/m2 3. All participants voluntarily participated in this study and signed informed consent

Exclusion criteria

Exclusion criteria: 1. Severe central or peripheral nervous system diseases; Severe respiratory or circulatory system diseases 2. Patients who have been taking anticoagulant drugs for a long time and have abnormal coagulation function; Patients with contraindications for nerve block such as infection and rash at the puncture site 3. History of allergies to relevant drugs 4. History of chronic pain, those who have used sedatives and analgesics within 24 hours before surgery 5. History of drug use, alcohol abuse, and substance abuse 6. Refusal to participate or inability to cooperate with the researcher in this study

Design outcomes

Primary

MeasureTime frame
Visual Analog Scale (VAS);

Secondary

MeasureTime frame
The dosage of sufentanil;Effective pressing frequency of analgesic pump;Number of times of remedial analgesia;Tumor necrosis factor alpha;Interleukin-26;T cell subpopulation (CD3+CD4+CD8+);Natural Killer Cells (NK);

Countries

China

Contacts

Public ContactGong Gu

The General Hospital of Western Theater Command

gonggu68@163.com+86 173 6013 7572

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026