Chronic periodontitis (CP)
Conditions
Interventions
Periodontal Basic Therapy Augmented with a Placebo Control Group:After brushing teeth in the morning and evening, rinse the mouth with a placebo solution.
Periodontal Basic Therapy Coupled with Probiotic Mouthwash Group:After completing dental cleansing in the morning and evening, utilize a postbiotic-infused oral rinsing solution for mouthwash.
Sponsors
Affiliated Stomatological Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Conforming to the Diagnostic Criteria for Chronic Periodontitis: A probing depth (PD) of >=4mm, clinical attachment loss (CAL) of >=2mm, and a positive result for bleeding on probing (BOP). 2. Individuals aged 18 to 60 years inclusive, of either sex. 3. With a minimum of twenty natural teeth retained in the oral cavity. 4. Having not undergone any recent comprehensive periodontal therapy; 5. The clinical records are comprehensive and intact, with no reported instances of food allergies or intolerances, and the individual has passed the medical examination with satisfactory results. 6. Exhibiting normal cognitive functioning, demonstrating robust adherence, possessing a comprehensive understanding of the trial, and voluntarily executing the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Coexisting with malignant neoplasms, autoimmune disorders, hematological conditions, and compromised hepatic and renal functionalities. 2.Afflicted with systemic conditions including hypertension, cardiovascular disease, and diabetes mellitus, among others. 3.Having undergone antibiotic therapy within the preceding month or with a necessity for antibiotic administration during the course of the study, and having participated in any clinical trials within the last 30 days. 4.Female individuals who are in the stages of gestation and lactation; 5.Presenting with malocclusion or suffering from occlusal trauma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing Depth(PD);Clinical Attachment Level (CAL); | — |
Secondary
| Measure | Time frame |
|---|---|
| Gingival Index;Bleeding on Probing (BOP);Plaque Index; | — |
Countries
China
Contacts
Public ContactYang Juanxia
Affiliated Stomatological Hospital of Nanchang University
Outcome results
None listed