Morbidly Obese
Conditions
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years old; 2.ASA Grade II-III; 3. Patients with BMI >=35kg/m^2 undergoing laparoscopic gastric volume reduction surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with known allergies to sugammadex, neostigmine + atropine, and ultrasonic coupling agent, as well as those with contraindications to their use; 2. Pulmonary organic diseases and respiratory tract and respiratory system diseases such as abnormal diaphragmatic function, massive pleural effusion, history of pulmonary resection, and severe pulmonary function abnormalities; 3. Neurological diseases (muscle spasm, myasthenia gravis, Lambert-Eaton syndrome); 4. Complicated with severe cardiovascular diseases (such as myocardial infarction, heart failure, arrhythmia, etc.), severe liver and kidney function abnormalities, acute and chronic alcoholism, and infectious diseases; 5. Chronic pain, long-term use of opioid analgesics, and psychotropic drugs; 6. Have a history of drug abuse, drug abuse, mental illness, communication disorders, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm excursion(DE); | — |
Secondary
| Measure | Time frame |
|---|---|
| Diaphragmatic Thickening Fraction;Duration from administration of the antagonist to extubation;Sedation-Agitation Scale(SAS);Hemodynamics during extubation;Incidence of hypoxia after extubation;Oxygenation index;Postoperative pulmonary complications;QoR-15 score;First postoperative exhaust and defecation time;Postoperative nausea and vomiting;Respiratory function;Adverse reaction;Length of hospital stay; | — |
Countries
China
Contacts
Public ContactGuanglei Wang
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed