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Effect of transcutaneous auricular vagus nerve stimulation on postoperative inflammation levels and neurocognition in elderly patients

Effect of transcutaneous auricular vagus nerve stimulation on postoperative inflammation levels and neurocognition in elderly patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094874
Enrollment
Unknown
Registered
2024-12-30
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative neurocognition

Interventions

Test group:Ranscutaneous auricular vagal nerve electricity

Sponsors

Shanghai Pudong New Area People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age 65-85 years old, regardless of gender; 2. American Society of Anesthesiologists (ASA) grade II ~ III, elective laparoscopic gastrointestinal tumor surgery; 3. Cognitive function is clear or mild cognitive impairment, and can cooperate with the completion of cognitive function tests; 4. Patients agreed to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Have a history of central nervous system diseases, such as brain and cerebral infarction, traumatic brain injury, epilepsy, etc.; 2. Have a history of mental illness or take related drugs; 3. Person implanted with a cardiac pacemaker. 4. Known or suspected severe atherosclerotic cardiovascular disease, severe carotid disease, heart failure, known severe coronary artery disease or recent myocardial infarction

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment Scale MoCA score;

Secondary

MeasureTime frame
Interleukin-1;Interleukin-6;C-reactive protein;Hamilton Depression Rating Scale-24;

Countries

China

Contacts

Public ContactMa Li

Shanghai Pudong New Area People's Hospital

904626725@qq.com+86 136 3631 7541

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026