Chronic Tonsillitis,Adenoid Hypertrophy
Conditions
Interventions
Dexmedetomidine intranasal administration group (D group).:Thirty minutes before surgery, the child is placed in a sitting position, the nasal cavity is cleaned, the spray nozzle is inserted into the
Lidocaine pump infusion group (L group):Thirty minutes before surgery, the child is seated and both nostrils are cleaned with saline spray. During anesthesia induction, 1.5mg/kg lidocaine (based on id
Dexmedetomidine intranasal administration combined with lidocaine pump infusion group (DL group):Thirty minutes before surgery, the child is placed in a sitting position. After cleaning the nasal cavi
Sponsors
First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: (1) ASA classification of grade I–II; (2) Children aged 2–12 years undergoing elective tonsillectomy and adenoidectomy in our hospital; (3) Body weight ranging from 19.4 to 28.0 kg; (4) Agree to participate in the study
Exclusion criteria
Exclusion criteria: (1) Abnormal liver or kidney function, history of heart disease, asthma, or central nervous system disorders; (2) Allergy to the study drugs; (3) History of anxiety, depression, or other psychiatric disorders, or sleep disturbances; (4) Behavioral and developmental disorders (e.g., attention deficit hyperactivity disorder or learning disabilities); (5) Severe cardiac conduction block (including sinoatrial, atrioventricular, or intraventricular block); (6) Wolff-Parkinson-White syndrome; (7) Structural abnormalities of the nasal cavity; (8) Use of other psychotropic drugs before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| perioperative sleep quality;postoperative pain scores ;vital signs;extubation time;incidence of delayed awakening;incidence of adverse events;PACU length of stay;surgery duration;intraoperative propofol and remifentanil dosages;intraoperative blood loss; | — |
Countries
China
Contacts
Public ContactLifang Zhan
First Affiliated Hospital of Gannan Medical University
Outcome results
None listed